Mast cell activation syndrome (MCAS) affects more than 15% of the U.S. population but evades most practitioners’ radar. Just five years ago, it wasn’t even on my radar, despite already having 20 years of experience as a clinician at that time. The more I dug (similar to leaky gut and post-COVID syndrome), the more I found my patients were suffering from this disorder.
Melanie Pincus, PhD
Dr. Melanie Blair Pincus is a neuroscientist, artist, and educator with a passion for crafting experiences that catalyze self-discovery and transformation. Melanie became interested in modalities that spur personal growth and rewire the brain during her PhD in neuroscience at Emory University, where she studied the legacy of early-life stress on the developing brain. She is compelled by both play and non-ordinary states of consciousness (NOSC) as powerful tools that promote flexible brain states for healing and flourishing. In her roles as chief scientific officer for two psychedelic startups, she has designed multi-omics psilocybin research programs with botanical mushrooms to explore the potential of NOSC for personal growth. Melanie’s new venture, Syncopy Design Lab (syncopydesignlab.com), is an experience design studio creating experiences that facilitate deeper states of connectedness to self, community, and the natural world. The lab weaves together transformative principles, biosensing technology, neuroaesthetic design, play, and NOSC to offer impactful art installations, workshops and retreats.