PPIs function by targeting and inhibiting the stomach’s acid-producing proton pumps, thereby reducing gastric acidity. This decrease in stomach acid can compromise the absorption of key nutrients, leading to deficiencies that could impact health if left unaddressed. The absorption of essential nutrients like vitamin B12, magnesium, calcium, and iron is particularly affected due to their reliance on gastric acid for optimal absorption.
Addressing Nutrient Deficiencies
Vitamin B12 Deficiency: Vitamin B12 is vital for neurological function, red blood cell production, and DNA synthesis. Its absorption is significantly impaired by reduced gastric acid, a common side effect of PPI use, potentially leading to anemia, fatigue, and neurological complications.
To counteract this, PPI users are advised to consider B12 supplementation, specifically in forms that are more readily absorbable and thus less dependent on gastric acid for absorption.1
Magnesium Deficiency: Playing a critical role in muscle and nerve functions, as well as bone health, magnesium deficiency can result from long-term PPI use. Symptoms can range from muscle cramps to seizures and cardiac arrhythmias. Incorporating magnesium-rich foods and supplements into one’s diet can help mitigate this risk, ensuring adequate magnesium levels.2
Calcium Deficiency: Calcium’s absorption is also hindered by reduced stomach acid levels, affecting bone health, muscle function, and nerve transmission. Adequate calcium intake, through dietary sources or supplements, is essential for individuals taking PPIs to prevent potential deficiencies and maintain bone density.1
Iron Deficiency: Iron is essential for oxygen transport and energy production. Reduced gastric acid from PPI usage can impair iron absorption, potentially leading to anemia. Addressing this through dietary adjustments or supplementation is crucial for maintaining adequate iron levels.2
The Importance of Dietary Supplementation With PPI Use
The nutrient deficiencies associated with PPI use highlight the importance of dietary supplementation. B12 supplements generally aim to provide targeted nutritional support for those affected by PPI-related nutrient deficiencies.
PPIs, while beneficial for treating acid-related disorders, necessitate a proactive approach to managing the associated risk of nutrient deficiencies through dietary supplementation. Incorporating supplements can provide essential nutritional support, ensuring the well-being of individuals on long-term PPI therapy.
References
Do you receive text messages from companies letting you know about offers or giveaways, or simply sharing news? If your answer is yes, then you have opted in for SMS (short message service) text-message marketing. SMS text-message marketing uses various platforms and software to send personalized, timely and sometimes interactive messages.
The Oregon College of Oriental Medicine (OCOM) has announced it is closing after 41 years. Pending accreditor approval, OCOM will cease offering classes after September (fourth-year OCOM students graduate Aug. 26). All current / incoming OCOM students have the option of continuing their education at the National University of Natural Medicine or Five Branches University, or transferring to another school altogether.
| Digital Exclusive
The end of cancer treatment does not necessarily signal a return to good health. Cancer survivors report poorer health and well-being than people who have not had cancer; many suffer chronic consequences of cancer and its treatments. Some may also develop new symptoms many years after treatment has ended.
